logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-106a
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line blood
Methods qRT-PCR, ELISA
Expression pattern down-regulated
Functional description Anti-angiogenic. Levels of miR-106a were negatively correlated with CEC levels pre-therapy. At week 17, after eight week of interferon-alfa-2b, levels of miR-106a increased. Blood levels of specific angioregulatory miRs are not associated with levels of angiogenic proteins.
PubMed ID 23217102
Year 2012
Title The association of blood angioregulatory microRNA levels with circulating endothelial cells and angiogenic proteins in patients receiving dacarbazine and interferon.
Drug-related ncRNA YES (interferon-alfa-2b)

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.